Background
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Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.
Alias Symbols: CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2
Protein Interaction Partner: FZR1,SMAD3,ABL1,BCAR1,BCAR3,CDH1,CHAT,CRK,CRKL,DIMT1L,ELSPBP1,FYN,ID2,ITCH,LCK,LYN,MICAL1,NCK1,NEDD9,PTK2,PTK2B,PTPN11,PTPN12,PXN,RAPGEF1,SH2D3C,SMAD1,SMAD2,SMAD3,TCF3,TRIP6,ZYX,ABL1,BCAR1,BCAR3,CDH1,CRK,CRKL,ELSPBP1,FYN,ID2,ITCH,LCK,LYN,MICAL1,NCK1,NEDD9,PTK2,PTK2B,PTPN12,PXN,RAPGEF1,SH2D3C,SMAD1,SMAD2,SMAD3,TRIP6,ZYX
Protein Size: 834
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