產(chǎn)品詳情

  • 產(chǎn)品名稱：EDG-6

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：KamiyaBiomedical
  • 產(chǎn)品文檔：
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簡單介紹：
EDG-6
詳情介紹：
Alternative Name EDG-6
Background EDG-6 Trnasfected Cell Positive Control Lysate. EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is a sphingosine-1- phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs.
Application Notes For use as a positive control with EDG-6 polyclonal antibody ABIN187788 for Western blot analysis. Use 10-20 μl of EDG-6 cell lysate per lane as a control when using EDG-6 antibody.
Restrictions For Research Use only
Format Liquid
Buffer Provided in 10% glycerol, 063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue and 5% 2-mercaptoethanol.
Storage -20 °C