產(chǎn)品詳情

  • 產(chǎn)品名稱：AKR1C3InhibitorI

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  • 產(chǎn)品廠商：Biovision
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簡單介紹：
AKR1C3InhibitorI
詳情介紹：
Purpose A highly potent and selective inhibitor of the type 5 17-beta-hydroxysteroid dehydrogenase AKR1C3.
Characteristics In repeat assays it showed an IC50of 0.013 ± 0.003 μM for AKR1C3, compared with 20.3 ± 3.8 μM against AKR1C1 and > 30 μM against AKR1C2 and AKR1C4. This inhibitor also showed displays potency in a cellular assay, blocking the ability of AKR1C3 to metabolize a proven substrate.
Purity ≥ 98?% by HPLC
Chemical Name 3-(3,4-Dihydroisoquinolin2(1H)-ylsulfonyl)benzoic acid
Formula C??H??NO?S
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 317.36 g/mol
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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