產(chǎn)品詳情

  • 產(chǎn)品名稱：AT56

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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AT56
詳情介紹：
Purpose A selective, competitive, and highly bioavailable inhibitor of L-PGDS (lipocalin-type prostaglandin D synthase)
Characteristics AT-56 is a selective, competitive, and highly bioavailable inhibitor of L-PGDS (lipocalin-type prostaglandin D synthase) (Ki = 75 μM). It inhibits the production of PGD2 by L-PGDS purified from human CSF and recombinant mouse cells with an IC?? value of 95 μM. At concentrations as high as 100 μM in vitro or 30 mg/kg in vivo, AT-56 does not affect the production of PGE2, PGF2α, or H-PGDS-catalyzed PGD2. PubChem CID: 11741525
Purity ≥ 98?% by HPLC
Chemical Name 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine
Formula C??H??N?
Permeability Cell-permeable
Solubility DMSO (>15 mg/ml)
Molecular Weight 397.52 g/mol
CAS-No 162640-98-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for AT 56 (ABIN1995158) AT 56